![Systemic Treatments for Metastatic Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Old Certainties and New Frontiers - Alessandro Rizzo, Antonio Cusmai, Raffaella Massafra, Samantha Bove, Maria Colomba Comes, Annarita Fanizzi, Gennaro Systemic Treatments for Metastatic Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Old Certainties and New Frontiers - Alessandro Rizzo, Antonio Cusmai, Raffaella Massafra, Samantha Bove, Maria Colomba Comes, Annarita Fanizzi, Gennaro](https://journals.sagepub.com/cms/10.1177/10732748221106267/asset/images/large/10.1177_10732748221106267-fig1.jpeg)
Systemic Treatments for Metastatic Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Old Certainties and New Frontiers - Alessandro Rizzo, Antonio Cusmai, Raffaella Massafra, Samantha Bove, Maria Colomba Comes, Annarita Fanizzi, Gennaro
![Table 2 from Luminal B breast cancer: molecular characterization, clinical management, and future perspectives. | Semantic Scholar Table 2 from Luminal B breast cancer: molecular characterization, clinical management, and future perspectives. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/5582615f848e686710455b6e112e876e1ab5fb5a/3-Table2-1.png)
Table 2 from Luminal B breast cancer: molecular characterization, clinical management, and future perspectives. | Semantic Scholar
![The therapeutic response of ER+/HER2− breast cancers differs according to the molecular Basal or Luminal subtype | npj Breast Cancer The therapeutic response of ER+/HER2− breast cancers differs according to the molecular Basal or Luminal subtype | npj Breast Cancer](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41523-020-0151-5/MediaObjects/41523_2020_151_Fig1_HTML.png)
The therapeutic response of ER+/HER2− breast cancers differs according to the molecular Basal or Luminal subtype | npj Breast Cancer
![Biomedicines | Free Full-Text | Breast Cancer Subtype-Specific miRNAs: Networks, Impacts, and the Potential for Intervention Biomedicines | Free Full-Text | Breast Cancer Subtype-Specific miRNAs: Networks, Impacts, and the Potential for Intervention](https://pub.mdpi-res.com/biomedicines/biomedicines-10-00651/article_deploy/html/images/biomedicines-10-00651-g001.png?1646999408)
Biomedicines | Free Full-Text | Breast Cancer Subtype-Specific miRNAs: Networks, Impacts, and the Potential for Intervention
![Envision Communications on X: "Doctors use genetic information about breast cancer cells to categorize breast cancers and help guide decisions about which treatments are best. Did you know Luminal B breast cancers Envision Communications on X: "Doctors use genetic information about breast cancer cells to categorize breast cancers and help guide decisions about which treatments are best. Did you know Luminal B breast cancers](https://pbs.twimg.com/media/FCK9anVXIAsS1ld.jpg:large)
Envision Communications on X: "Doctors use genetic information about breast cancer cells to categorize breast cancers and help guide decisions about which treatments are best. Did you know Luminal B breast cancers
![Ki‑67 index value and progesterone receptor status can predict prognosis and suitable treatment in node‑negative breast cancer patients with estrogen receptor‑positive and HER2‑negative tumors Ki‑67 index value and progesterone receptor status can predict prognosis and suitable treatment in node‑negative breast cancer patients with estrogen receptor‑positive and HER2‑negative tumors](https://www.spandidos-publications.com/article_images/ol/17/1/ol-17-01-0616-g00.jpg)
Ki‑67 index value and progesterone receptor status can predict prognosis and suitable treatment in node‑negative breast cancer patients with estrogen receptor‑positive and HER2‑negative tumors
![The CINSARC signature predicts the clinical outcome in patients with Luminal B breast cancer | npj Breast Cancer The CINSARC signature predicts the clinical outcome in patients with Luminal B breast cancer | npj Breast Cancer](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41523-021-00256-2/MediaObjects/41523_2021_256_Fig1_HTML.png)
The CINSARC signature predicts the clinical outcome in patients with Luminal B breast cancer | npj Breast Cancer
![Luminal A and luminal B (HER2 negative) subtypes of breast cancer consist of a mixture of tumors with different genotype | BMC Research Notes | Full Text Luminal A and luminal B (HER2 negative) subtypes of breast cancer consist of a mixture of tumors with different genotype | BMC Research Notes | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2F1756-0500-5-376/MediaObjects/13104_2011_Article_1552_Fig1_HTML.jpg)
Luminal A and luminal B (HER2 negative) subtypes of breast cancer consist of a mixture of tumors with different genotype | BMC Research Notes | Full Text
![Luminal Breast Cancer: Risk of Recurrence and Tumor-Associated Immune Suppression | Molecular Diagnosis & Therapy Luminal Breast Cancer: Risk of Recurrence and Tumor-Associated Immune Suppression | Molecular Diagnosis & Therapy](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs40291-021-00525-7/MediaObjects/40291_2021_525_Fig1_HTML.png)
Luminal Breast Cancer: Risk of Recurrence and Tumor-Associated Immune Suppression | Molecular Diagnosis & Therapy
![Luminal B breast cancer: molecular characterization, clinical management, and future perspectives. | Semantic Scholar Luminal B breast cancer: molecular characterization, clinical management, and future perspectives. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/5582615f848e686710455b6e112e876e1ab5fb5a/2-Table1-1.png)
Luminal B breast cancer: molecular characterization, clinical management, and future perspectives. | Semantic Scholar
![CORALLEEN phase 2 trial: Neoadjuvant Ribociclib plus Letrozole in Early Stage HR positive, Her2 negative, Luminal CORALLEEN phase 2 trial: Neoadjuvant Ribociclib plus Letrozole in Early Stage HR positive, Her2 negative, Luminal](https://image.slidesharecdn.com/coralleentrialautosaved-200211202300/85/coralleen-phase-2-trial-neoadjuvant-ribociclib-plus-letrozole-in-early-stage-hr-positive-her2-negative-luminal-b-breast-cancer-3-320.jpg?cb=1672803264)
CORALLEEN phase 2 trial: Neoadjuvant Ribociclib plus Letrozole in Early Stage HR positive, Her2 negative, Luminal
![Frontiers | High Parity Predicts Poor Outcomes in Patients With Luminal B-Like (HER2 Negative) Early Breast Cancer: A Prospective Finnish Single-Center Study Frontiers | High Parity Predicts Poor Outcomes in Patients With Luminal B-Like (HER2 Negative) Early Breast Cancer: A Prospective Finnish Single-Center Study](https://www.frontiersin.org/files/Articles/539252/fonc-10-01470-HTML/image_m/fonc-10-01470-t005.jpg)
Frontiers | High Parity Predicts Poor Outcomes in Patients With Luminal B-Like (HER2 Negative) Early Breast Cancer: A Prospective Finnish Single-Center Study
![Biological subtype predicts locoregional recurrence after postmastectomy radiotherapy in Chinese breast cancer patients - Wang - 2020 - Cancer Medicine - Wiley Online Library Biological subtype predicts locoregional recurrence after postmastectomy radiotherapy in Chinese breast cancer patients - Wang - 2020 - Cancer Medicine - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/0a765031-1273-4bcb-94c4-ce9a473f2847/cam42904-fig-0001-m.jpg)